Pathology and genetics of tumours of the digestive system

  title={Pathology and genetics of tumours of the digestive system},
  author={Stanley R. Hamilton and Lauri A. Aaltonen},

Ekspresi Vascular Endothelial Growth Factor Berhubungan Positif dengan Kedalaman Invasi pada Adenokarsinoma Kolorektal

Tujuan penelitian ini untuk menganalisishubungan antara ekspresi VEGF dan kedalaman invasi pada adenokarsinoma kolorektal yang terjadi di seluruhdunia dan merupakan masalah kesehatan serius di Indonesia.

Impact of Nutritional Status on Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET) Aggressiveness

This is the first study reporting an association between nutritional status and tumor aggressiveness in a selected group of GEP-NETs and higher intakes of food of MD, may represent a potential tool for prevention of tumor aggressivity.

An Overview of Autosomal Dominant Tumour Syndromes with Prominent Features in the Oral and Maxillofacial Region

The pertinent features of autosomal dominant inherited tumour syndromes are reviewed with a systems-based approach, emphasising their clinical impact and diagnosis.

Evaluation of Expression of Her2/neu in Gastric Cancer and Its Significance as a Prognostic Factor in Gastric Adenocarcinoma

Her2 neu expression is more in Oesophageal gastric junctional tumours & corpus location of stomach tumours (35.3%) compared to Pylorus-Antral tumours, and also the presence of HER-2/neu expression in patients with signet ring cell carcinoma (40% compared to Non signetRing cell carcinomas) is observed.

Absence of either gastric or intestinal phenotype in microscopic differentiated gastric carcinomas

The phenotypes of the carcinomas and their surrounding mucosa were unrelated, suggesting that DGCs may arise from gastric mucosa affected by intestinal metaplasia or not, without having either the gastric or intestinal phenotype.

Evaluation and Analysis of Colon Cancer in Kingdom of Bahrain: A Retrospective Study in a Tertiary Care Center

Due to lack of colorectal screening, Bahrain has a higher proportion of advanced stage cancer at presentation and this will help in reducing the mortality and improving the patient prognosis by proper screening and genetic testing.

Mucinous cystic neoplasms of the liver: presence of biliary communication

A 35-year-old woman referred for a symptomatic liver mass was diagnosed with low-grade mucinous cystic neoplasm of the liver (MCN-L), which has not been elucidated due to its rarity.



Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

The involvement of mismatch repair deficiency in the premalignant stage of tumorigenesis in HNPCC cases is suggested, and it is suggested that mismatch repair genes (MSH2 or others) are defective in the germline of nearly all these patients.

beta-catenin is a target for the ubiquitin-proteasome pathway.

It is shown that ubiquitination of beta-catenin is greatly reduced in Wnt-expressing cells, providing the first evidence that the ubiquitin-proteasome degradation pathway may act downstream of GSK3beta in the regulation of Beta-Catenin.

Features of gastric cancer in hereditary non‐polyposis colorectal cancer syndrome

The results support the view that gastric cancer belongs to the tumor spectrum of HNPCC, and the intestinal type of histology is characteristic, as is the RER+ phenotype, but H. pylori infection was rare.

Perineal and perirectal sarcomas : Report of two cases

Perineal and perirectal sarcomas are generally of poor prognosis mainly because of delayed diagnosis, but Computed tomography and magnetic resonance imaging can be extremely useful to help assess these tumors.

E-Cadherin Expression Is Correlated with the Isolated Cell/Diffuse Histotype and with Features of Biological Aggressiveness of Gastric Carcinoma

It is concluded that abnormal E-cadherin expression is correlated with diffuse/isolated-cell histotype and features of biological aggressiveness of gastric carcinoma.