Pathology and MRI: exploring cognitive impairment in MS.

  title={Pathology and MRI: exploring cognitive impairment in MS.},
  author={Friedemann Paul},
  journal={Acta neurologica Scandinavica},
  volume={134 Suppl 200},
Cognitive impairment is a frequent symptom in people with multiple sclerosis, affecting up to 70% of patients. This article reviews the published association of cognitive dysfunction with neuroimaging findings. Cognitive impairment has been related to focal T2 hyperintense lesions, diffuse white matter damage and corical and deep gray matter atrophy. Focal lesions cannot sufficiently explain cognitive dysfunction in MS; microstructural tissue damage detectable by diffusion tensor imaging and… CONTINUE READING
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