Pathological studies of chickens experimentally infected with two highly pathogenic avian influenza viruses.

@article{Kobayashi1996PathologicalSO,
  title={Pathological studies of chickens experimentally infected with two highly pathogenic avian influenza viruses.},
  author={Y. Kobayashi and T. Horimoto and Y. Kawaoka and D. Alexander and C. Itakura},
  journal={Avian pathology : journal of the W.V.P.A},
  year={1996},
  volume={25 2},
  pages={
          285-304
        }
}
Lesions of chickens inoculated with two highly pathogenic avian influenza virus strains, A/turkey/England/50-92/91 (H5N1) and A/chicken/Victoria/1/85 (H7N7) were examined histologically and immunohistochemically. Birds of both treatment groups died within 5 days post-inoculation. The most significant lesions induced by these two viruses consisted of swelling of the microvascular endothelium, systemic congestion, multifocal haemorrhages, perivascular mononuclear cell infiltration, and thrombosis… Expand
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