Pathological niche environment transforms dermal stem cells to keloid stem cells: a hypothesis of keloid formation and development.


Keloid is a disease that is difficult to cure because of its high recurrence rate after chemotherapy or radiotherapy, therefore it is considered as a benign skin tumor. Tumor stem cells are proposed as the source for tumor development and post-therapy recurrence. Interestingly, keloid stem cells have also been discovered, which share some characters with… (More)
DOI: 10.1016/j.mehy.2013.08.033


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