Pathological consequences of intermittent hypoxia in the central nervous system.

@article{Zhang2012PathologicalCO,
  title={Pathological consequences of intermittent hypoxia in the central nervous system.},
  author={Shelley X. L. Zhang and Yang Wang and David Gozal},
  journal={Comprehensive Physiology},
  year={2012},
  volume={2 3},
  pages={
          1767-77
        }
}
Intermittent hypoxia (IH) is a frequent occurrence in clinical settings. In the last decades, evidence has emerged implicating the gas exchange alterations and sleep disruption associated with those disorders in the high prevalence of cognitive and behavioral deficits afflicting these patients. In an effort to better characterize the role of IH, and to identify potential mechanisms of IH-induced central nervous system (CNS) dysfunction, a large number of rodent models have been recently… CONTINUE READING
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