Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment.

@article{Marzo2004PathologicalAM,
  title={Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment.},
  author={Angelo M De Marzo and Theodore L Deweese and Elizabeth A. Platz and Alan K Meeker and Masashi Nakayama and Jonathan I. Epstein and William B Isaacs and William Andrew Nelson},
  journal={Journal of cellular biochemistry},
  year={2004},
  volume={91 3},
  pages={459-77}
}
Prostate cancer is an increasing threat throughout the world. As a result of a demographic shift in population, the number of men at risk for developing prostate cancer is growing rapidly. For 2002, an estimated 189,000 prostate cancer cases were diagnosed in the U.S., accompanied by an estimated 30,200 prostate cancer deaths [Jemal et al., 2002]. Most prostate cancer is now diagnosed in men who were biopsied as a result of an elevated serum PSA (>4 ng/ml) level detected following routine… CONTINUE READING

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