Pathological analysis of local delivery of paclitaxel via a polymer-coated stent.


BACKGROUND Paclitaxel can inhibit vascular smooth muscle proliferation in vitro, and early studies suggest that paclitaxel may be useful in preventing restenosis. Early and late intimal growth and local vascular pathological changes associated with paclitaxel delivered via stents have not been fully explored. METHODS AND RESULTS Localized drug delivery… (More)


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