Pathological O2 supply dependence of diaphragmatic and systemic O2 uptake during endotoxemia.

@article{Kim1994PathologicalOS,
  title={Pathological O2 supply dependence of diaphragmatic and systemic O2 uptake during endotoxemia.},
  author={Won Shik Kim and Michael Ward and Sabah N. A. Hussain},
  journal={Journal of applied physiology},
  year={1994},
  volume={77 3},
  pages={1093-100}
}
Our aim was to assess whether endotoxemia impairs the ability of the diaphragm to extract O2 and whether this defect leads to a greater dependence of O2 uptake on O2 delivery. In two groups of anesthetized mechanically ventilated dogs, the left hemidiaphragm was vascularly isolated. Diaphragmatic blood flow and cardiac output (CO) were measured… CONTINUE READING