Pathological Display of Affect in Patients with Depression and Right Frontal Brain Damage: An Alternative Mechanism

  title={Pathological Display of Affect in Patients with Depression and Right Frontal Brain Damage: An Alternative Mechanism},
  author={Elliott D. Ross and Rege S. Stewart},
  journal={The Journal of Nervous and Mental Disease},
  • E. Ross, R. S. Stewart
  • Published 1 March 1987
  • Psychology, Medicine, Biology
  • The Journal of Nervous and Mental Disease
Two patients are reported with the acute onset of pathological crying following right inferior frontal brain damage. Both had severe endogenous depession and neither had pseudobulbar palsy. These and other cases argue that two organic brain diseases—one structural and the other “physiopharmacological”—may interact to produce pathological display of affect that cannot be accounted for by traditional neurological explanations. A pharmacological mechanism for the rapid amelioration of pathological… 

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