Pathological Confirmation of Optic Neuropathy in Familial Dysautonomia.

@article{MendozaSantiesteban2017PathologicalCO,
  title={Pathological Confirmation of Optic Neuropathy in Familial Dysautonomia.},
  author={Carlos E. Mendoza-Santiesteban and Jose-Alberto Palma and Thomas Hedges and Nora M V Laver and Nada A Farhat and Lucy Jane Norcliffe-Kaufmann and Horacio Kaufmann},
  journal={Journal of neuropathology and experimental neurology},
  year={2017},
  volume={76 3},
  pages={238-244}
}
Clinical data suggest that optic neuropathy and retinal ganglion cell loss are the main cause of visual decline in patients with familial dysautonomia, but this has not previously been confirmed by pathological analyses. We studied retinas and optic nerves in 6 eyes from 3 affected patients obtained at autopsy. Analyses included routine neurohistology and… CONTINUE READING