Pathologic rupture of the spleen as the initial manifestation of acute lymphoblastic leukemia: an additional case.

@article{RodrguezLuaces1998PathologicRO,
  title={Pathologic rupture of the spleen as the initial manifestation of acute lymphoblastic leukemia: an additional case.},
  author={Marta Rodr{\'i}guez-Luaces and C Jim{\'e}nez Herrainz and A Lafuente Guijosa and P Mateos Rubio and J M Hern{\'a}ndez-Bayo and Fernando Hern{\'a}ndez-Navarro},
  journal={Haematologica},
  year={1998},
  volume={83 4},
  pages={383-4}
}
Pathological rupture of the spleen (PRS) is a rare, but well known complication of some hematological malignancies. In a recent review of the literature, Giagounidis et al. Identified 136 cases of pathologic rupture of the spleen since 1861. This number gives an idea of how seldom it occurs. In this review, 34% of the cases had occurred in acute leukemias, and 13% in acute lymphoblastic leukemias. In most cases, PRS occurs on the course of the disease. PRS as initial manifestation of ALL is a… CONTINUE READING