Pathologic roles of prorenin and (pro)renin receptor in the eye.


Recent reports indicated that tissue renin-angiotensin system (RAS) was upregulated and angiotensin II type 1 receptor signaling plays crucial roles in ocular inflammation and neovascularization; however, the precise mechanism for activating tissue RAS had not been defined until recently. (Pro)renin receptor, a recently identified molecule existing in the… (More)

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@article{Satofuka2008PathologicRO, title={Pathologic roles of prorenin and (pro)renin receptor in the eye.}, author={Shingo Satofuka and Atsuhiro Ichihara and Norihiro Nagai and Kazuo Tsubota and Hiroshi Itoh and Susumu Ishida}, journal={Frontiers in bioscience : a journal and virtual library}, year={2008}, volume={13}, pages={3884-95} }