Pathologic response of the pancreas and duodenum to experimental intraoperative irradiation.

@article{AhmaduSuka1988PathologicRO,
  title={Pathologic response of the pancreas and duodenum to experimental intraoperative irradiation.},
  author={F Ahmadu-Suka and Edward L Gillette and Stephen J. Withrow and Paul Husted and A W Nelson and Cole Whiteman},
  journal={International journal of radiation oncology, biology, physics},
  year={1988},
  volume={14 6},
  pages={1197-204}
}
The pancreas and duodenum of 24 beagle dogs were given intraoperative irradiation (IORT) with 6 MeV electrons. The dose range was 17.5 Gy to 40 Gy. Billroth II gastrojejunostomy was performed on all dogs prior to irradiation. Six control dogs received only Billroth II surgery. Starting 2 weeks after surgery, dogs in the irradiation groups were given 50 Gy 6 MV X rays external beam radiation therapy (EBRT) to the pancreas and duodenum. The total dose of 50 Gy was given in 2 Gy fractions over 5… CONTINUE READING

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