Pathogens and immunologic memory in asthma: what have we learned?


Animal models and clinical studies of asthma have generated important insights into the first effector phase leading to the development of allergic airway disease and bronchial hyper-reactivity. In contrast, mechanisms related to asthma chronicity or persistence are less well understood. The CD4(+) T-helper 2 lymphocytes are known initiators of the… (More)
DOI: 10.1586/1744666X.1.4.589


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