Pathogenicity of tick-borne encephalitis virus isolated in Hokkaido, Japan in mouse model.

@article{Chiba1999PathogenicityOT,
  title={Pathogenicity of tick-borne encephalitis virus isolated in Hokkaido, Japan in mouse model.},
  author={Naokazu Chiba and Takuya Iwasaki and Tetsuya Mizutani and Hiroaki Kariwa and T. Kurata and Ikuo Takashima},
  journal={Vaccine},
  year={1999},
  volume={17 7-8},
  pages={779-87}
}
The pathogenic characteristics of tick-borne encephalitis (TBE) virus strain (Oshima 5-10) isolated from a sentinel dog in Hokkaido, Japan, was compared by use of a mouse model with several inoculation routes to other strains of TBE virus (the Far Eastern subtype; Sofjin strain and the Western subtype; Hochosterwitz strain) and TBE complex virus (Langat virus; TP-21 strain). The degree of neuroinvasiveness of the strains in mice subcutaneously (s.c.) inoculated was Sofjin equaled Hochosterwitz… CONTINUE READING

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