Pathogenicity islands and phages in Vibrio cholerae evolution.

@article{Faruque2003PathogenicityIA,
  title={Pathogenicity islands and phages in Vibrio cholerae evolution.},
  author={Shah M. Faruque and John J Mekalanos},
  journal={Trends in microbiology},
  year={2003},
  volume={11 11},
  pages={505-10}
}
The identification of accessory genetic elements (plasmids, phages and chromosomal 'pathogenicity islands') encoding virulence-associated genes has facilitated our efforts to understand the origination of pathogenic microorganisms. Toxigenic Vibrio cholerae, the etiologic agent of cholera, represents a paradigm for this process in that this organism evolved from environmental nonpathogenic V. cholerae by acquisition of virulence genes. The major virulence genes in V. cholerae, which are… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 47 references

CTXF-independent production of RS1 satellite phage by Vibrio cholerae

Faruque, S.M
Proc. Natl. Acad. Sci. U. S. A • 2003

Emergence and evolution of Vibrio cholerae O139.

Proceedings of the National Academy of Sciences of the United States of America • 2003

Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease

M Dziejman
Proc. Natl. Acad. Sci. U. S. A • 2002

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