Pathogenic role of macrophages in intradermal infection of methicillin-resistant Staphylococcus aureus in thermally injured mice.

@article{Asai2010PathogenicRO,
  title={Pathogenic role of macrophages in intradermal infection of methicillin-resistant Staphylococcus aureus in thermally injured mice.},
  author={Akira Asai and Yasuhiro Tsuda and Makiko Kobayashi and Toshiaki Hanafusa and David N . Herndon and Fujio Suzuki},
  journal={Infection and immunity},
  year={2010},
  volume={78 10},
  pages={4311-9}
}
Intradermal infection of methicillin-resistant Staphylococcus aureus (MRSA) in burned mice was pathogenically analyzed. An abscess was formed in normal mice intradermally infected with 10(8) CFU/mouse of MRSA, and all of these mice survived after the infection; however, abscess formation was not demonstrated to occur in burned mice similarly exposed to the pathogen, and all of these mice died within 5 days of infection. In burned mice, MRSA infected at the burn site intradermal tissues spread… CONTINUE READING

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