Pathogenic mechanisms of HIV disease.

@article{Moir2011PathogenicMO,
  title={Pathogenic mechanisms of HIV disease.},
  author={Susan Moir and Tae-Wook Chun and Anthony S. Fauci},
  journal={Annual review of pathology},
  year={2011},
  volume={6},
  pages={223-48}
}
Human immunodeficiency virus (HIV) infection is generally characterized by inefficient viral transmission; an acute phase of intense viral replication and dissemination to lymphoid tissues; a chronic, often asymptomatic phase of sustained immune activation and viral replication; and an advanced phase of marked depletion of CD4(+) T cells that leads to acquired immune deficiency syndrome. Major insight into HIV transmission and each phase of infection has been gained from studies on blood and… CONTINUE READING
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