Pathogenic mechanism of second hand smoke induced inflammation and COPD

  title={Pathogenic mechanism of second hand smoke induced inflammation and COPD},
  author={Rahel L. Birru and Yuanpu Peter Di},
  booktitle={Front. Physio.},
Second hand smoke (SHS) introduces thousands of toxic chemicals into the lung, including carcinogens and oxidants, which cause direct airway epithelium tissue destruction. It can also illicit indirect damage through its effect on signaling pathways related to tissue cell repair and by the abnormal induction of inflammation into the lung. After repeated exposure to SHS, these symptoms can lead to the development of pulmonary inflammatory disorders, including chronic obstructive pulmonary disease… CONTINUE READING


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