Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs.

@article{Busnelli2009PathogeneticRO,
  title={Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs.},
  author={Marco Busnelli and Alberto Froio and Maria Laura Bacci and Massimo Giunti and Maria Grazia Cerrito and Roberto Giovannoni and Monica Forni and Fabio Gentilini and Alessandra Scagliarini and Gaetano Deleo and Cristian Benatti and Biagio Eugenio Leone and Giorgio Maria Biasi and Marialuisa Lavitrano},
  journal={Atherosclerosis},
  year={2009},
  volume={207 2},
  pages={384-90}
}
OBJECTIVE Most strategies against intimal hyperplasia developed in several preclinical models failed in terms of clinical application, often due to a discrepancy between animal and human disease. The aim of this study was to setup for the first time a porcine vascular injury model with mild hypercholesterolemia able to significantly increase the degree of… CONTINUE READING