Pathogenetic role of autoantibodies in neurological diseases

@article{Archelos2000PathogeneticRO,
  title={Pathogenetic role of autoantibodies in neurological diseases},
  author={Juan J. Archelos and H. P. Hartung},
  journal={Trends in Neurosciences},
  year={2000},
  volume={23},
  pages={317-327}
}
Autoreactive B cells and antibodies can be detected in a variety of neurological diseases. Their causative role has been established in some disorders and they are obviously involved in the pathogenesis of others. Some mechanisms engendering B-cell autoimmunity in animal models have been shown to operate in humans. Factors that determine B-cell immune-response patterns and the effector pathways have been identified. B-cell responses to CNS-restricted autoantigens are governed by distinctive… Expand
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