Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention.

@article{Kramer2011PathogeneticMO,
  title={Pathogenetic mechanisms of posttraumatic osteoarthritis: opportunities for early intervention.},
  author={William Clinton Kramer and Kelly J. Hendricks and Jinxi Wang},
  journal={International journal of clinical and experimental medicine},
  year={2011},
  volume={4 4},
  pages={
          285-98
        }
}
Osteoarthritis (OA) is characterized by joint pain and stiffness with radiographic evidence of joint space narrowing, osteophytes, and subchondral bone sclerosis. Posttraumatic OA (PTOA) arises from joint trauma, which accounts for a fraction of all patients with OA. Articular cartilage breakdown can occur soon or for years after a joint injury. Even with the current care of joint injuries, such as anatomic reduction and rigid fixation of intra-articular fractures and reconstruction of ruptured… CONTINUE READING

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