Pathogenetic mechanisms of congenital cardiovascular malformations revisited.

  title={Pathogenetic mechanisms of congenital cardiovascular malformations revisited.},
  author={Elizabeth K. Bailey Clark},
  journal={Seminars in perinatology},
  volume={20 6},
Rapid advances in cardiovascular science have expanded our knowledge of the mechanisms of heart development. Epidemiologists have defined the prevalence of congenital cardiovascular malformations, developmental biologists have delineated cascades of cell lineage, and molecular geneticists have identified mutations and loci associated with familial heart and vascular defects. We are well on the way to a molecular understanding of congenital cardiovascular malformations. Thus, it seems… CONTINUE READING

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