Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both.

@article{Pouleur2010PathogenesisOS,
  title={Pathogenesis of sudden unexpected death in a clinical trial of patients with myocardial infarction and left ventricular dysfunction, heart failure, or both.},
  author={Anne-Catherine M Pouleur and Ebrahim Barkoudah and Hajime Uno and Hicham Skali and Peter V. Finn and Steven L. Zelenkofske and Yu. N. Belenkov and Viacheslav Mareev and Eric J. Velazquez and Jean Lucien Rouleau and Aldo Pietro Maggioni and Lars Valeur K{\o}ber and Robert M. Califf and John J V McMurray and Marc A. Pfeffer and Scott David Solomon},
  journal={Circulation},
  year={2010},
  volume={122 6},
  pages={
          597-602
        }
}
BACKGROUND The frequency of sudden unexpected death is highest in the early post-myocardial infarction (MI) period; nevertheless, 2 recent trials showed no improvement in mortality with early placement of an implantable cardioverter-defibrillator after MI. METHODS AND RESULTS To better understand the pathophysiological events that lead to sudden death after MI, we assessed autopsy records in a series of cases classified as sudden death events in patients from the VALsartan In Acute myocardial… CONTINUE READING

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