Pathogenesis of primary chronic venous disease: Insights from animal models of venous hypertension.

Abstract

BACKGROUND Reflux of blood through incompetent venous valves is a major cause of the venous hypertension that underlies clinical manifestations of chronic venous disease, including varicose veins, lipodermatosclerosis, and venous ulcers. OBJECTIVE To review published literature relating to animal models in which venous hypertension has been produced and… (More)
DOI: 10.1016/j.jvs.2007.09.028

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Cite this paper

@article{Bergan2008PathogenesisOP, title={Pathogenesis of primary chronic venous disease: Insights from animal models of venous hypertension.}, author={John J. Bergan and Luigi Pascarella and Geert W. Schmid-Schoenbein}, journal={Journal of vascular surgery}, year={2008}, volume={47 1}, pages={183-92} }