Pathogenesis of porcine Actinobacillus pleuropneumonia, part II: roles of proinflammatory cytokines.

@article{Huang1999PathogenesisOP,
  title={Pathogenesis of porcine Actinobacillus pleuropneumonia, part II: roles of proinflammatory cytokines.},
  author={Hongsheng Huang and Andrew A. Potter and M. C. R. Moura Campos and Fredrick A Leighton and Philip James Willson and Deborah M. Haines and William G. Yates},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={1999},
  volume={63 1},
  pages={69-78}
}
The in vitro production of proinflammatory cytokines after stimulation with Actinobacillus pleuropneumoniae and the relation of these cytokines in vivo with the disease caused by A. pleuropneumoniae were investigated. Within 24 h, in vitro stimulation by A. pleuropneumoniae (serotype 1) preparations, including killed bacteria, bacterial culture supernatant, lipopolysaccharide, and bacterial extracts, porcine pulmonary alveolar macrophages (PAM) produced significant (P < 0.05) amounts of tumor… CONTINUE READING

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