Pathogenesis of lymphangiomas

  title={Pathogenesis of lymphangiomas},
  author={Susanne Wiegand and Behfar Eivazi and Peter Josef Barth and Dirk Berens von Rautenfeld and Benedikt Josef Folz and Robert Mandic and Jochen Werner},
  journal={Virchows Archiv},
Based on various hypotheses concerning lymphangiogenesis published in the literature, different putative mechanisms of lymphangioma development are discussed including failure of the lymphatic system to connect with or separate from the venous system, abnormal budding of the lymphatic system from the cardinal vein, or acquired processes such as traumata, infections, chronic inflammations, and obstructions. Increasingly, the possible influence of lymphangiogenic growth factors on the development… CONTINUE READING


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