Pathogenesis of intestinal strictures in Crohn's disease-an update.

@article{Graham1995PathogenesisOI,
  title={Pathogenesis of intestinal strictures in Crohn's disease-an update.},
  author={Martin F. Graham},
  journal={Inflammatory bowel diseases},
  year={1995},
  volume={1 3},
  pages={
          220-7
        }
}
: Stricture formation in Crohn's disease is a complication of an important wound healing process in the intestine. The smooth muscle cells of the intestinal musculares bear a responsibility for the repair of injured intestine, and effect this wound healing process by proliferating and laying down collagen at the site of injury. Injury in the submucosa, and chronicity of injury, are important factors in the development of stricture. The resultant accumulation of collagenous scar, thickening of… CONTINUE READING

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