Pathogenesis of inflammatory periodontal disease. A summary of current work.

  title={Pathogenesis of inflammatory periodontal disease. A summary of current work.},
  author={Roy C. Page and Hubert E. Schroeder},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  volume={34 3},
Chronic periodontitis, a common disease of microbial origin, is the major cause of tooth loss in adult humans. The disease serves as a convenient experimental model for analysis of many aspects of chronic inflammation. A consideration of currently available data has permitted the formulation of a new concept of the pathogenesis of this disease. The gingival tissues respond within 2 to 4 days to a beginning accumlation of microbial plaque with a classic acute exudative vasculitis which we have… CONTINUE READING


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