Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.

@article{Fontana2014PathogenesisOI,
  title={Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.},
  author={Robert J Fontana},
  journal={Gastroenterology},
  year={2014},
  volume={146 4},
  pages={914-28}
}
Idiosyncratic drug-induced liver injury (DILI) is a rare disease that develops independently of drug dose, route, or duration of administration. Furthermore, idiosyncratic DILI is not a single disease entity but rather a spectrum of rare diseases with varying clinical, histological, and laboratory features. The pathogenesis of DILI is not fully understood… CONTINUE READING