Pathogenesis of idiopathic pulmonary fibrosis.

  title={Pathogenesis of idiopathic pulmonary fibrosis.},
  author={Paul J Wolters and Harold R. Collard and Kirk D. Jones},
  journal={Annual review of pathology},
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with aging that is characterized by the histopathological pattern of usual interstitial pneumonia. Although an understanding of the pathogenesis of IPF is incomplete, recent advances delineating specific clinical and pathologic features of IPF have led to better definition of the molecular pathways that are pathologically activated in the disease. In this review we highlight several of these advances, with a… CONTINUE READING
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