Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatment.

@article{Garrity2006PathogenesisOG,
  title={Pathogenesis of graves ophthalmopathy: implications for prediction, prevention, and treatment.},
  author={James A. Garrity and Rebecca S. Bahn},
  journal={American journal of ophthalmology},
  year={2006},
  volume={142 1},
  pages={147-153}
}
PURPOSE To review current concepts regarding the pathogenesis of Graves ophthalmopathy (GO). We have presented this information in the context of potential target sites for novel disease therapies. DESIGN Review of recent literature. METHODS Synthesis of recent literature. RESULTS Enlargement of the extraocular muscle bodies and expansion of the orbital fatty connective tissues is apparent in patients with GO. These changes result from abnormal hyaluronic acid accumulation and edema… CONTINUE READING
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