Pathogenesis of foot-and-mouth disease in swine, studied by in-situ hybridization.

@article{Brown1995PathogenesisOF,
  title={Pathogenesis of foot-and-mouth disease in swine, studied by in-situ hybridization.},
  author={Corrie C. Brown and Heikki Olander and Richard F. Meyer},
  journal={Journal of comparative pathology},
  year={1995},
  volume={113 1},
  pages={
          51-8
        }
}
Eight 7-month-old pigs were inoculated intradermally with 10(3) plaque-forming units of foot-and-mouth disease virus, type O, and killed 24, 48, 72, or 96 h later. Numerous tissues from each animal were collected and examined histopathologically and by in-situ hybridization to determine the presence of virus and its correlation with lesion development. The probe for in-situ hybridization was a biotinylated 500-base negative-sense transcription product corresponding to a portion of the gene… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

Pathology and viral distributions of the porcinophilic foot-and-mouth disease virus strain (O/Taiwan/97) in experimentally infected pigs.

  • Transboundary and emerging diseases
  • 2009
VIEW 4 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

The pathogenesis and diagnosis of foot-and-mouth disease.

  • Journal of comparative pathology
  • 2003
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

Type III interferon protects swine against foot-and-mouth disease.

  • Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
  • 2014