Pathogenesis of experimental liver cancer: comparison with humans.

  • Emmanuel Farber
  • Published 1987 in
    Archives of toxicology. Supplement. = Archiv fur…


The multi-step nature of cancer development in the liver with chemical carcinogens is very well developed in the rat and is highly probable in humans and in mice. Since this step-by-step analysis of hepatocarcinogenesis is much more advanced in the rat than in the other two species, the pathogenesis in the rat will be briefly reviewed. Initiation steps I… (More)


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