Pathogenesis of encephalomyocarditis virus (EMCV) infection in piglets during the viraemia phase: a histopathological, immunohistochemical and virological study.

@article{Papaioannou2003PathogenesisOE,
  title={Pathogenesis of encephalomyocarditis virus (EMCV) infection in piglets during the viraemia phase: a histopathological, immunohistochemical and virological study.},
  author={Nikolaos G Papaioannou and Charalambos Billinis and Vasileios Psychas and Orestis Papadopoulos and Ioannis Vlemmas},
  journal={Journal of comparative pathology},
  year={2003},
  volume={129 2-3},
  pages={161-8}
}
Six piglets aged 20 days were inoculated oranasally with 5 ml of a suspension (10(6) TCID(50)/ml) of a Greek myocardial strain of encephalomyocarditis virus (EMCV). The animals either died (n=2) or were killed for examination on days 1,2 or 3 post-inoculation (pi). EMCV was isolated from virtually all organs examined (heart, tonsils, palatine glands, pancreas, spleen, small intestine and mesenteric lymph nodes). Histopathologically, interstitial myocarditis, necrosis of cardiac muscle cells and… CONTINUE READING