Pathogenesis of acute respiratory illness caused by human parainfluenza viruses.

  title={Pathogenesis of acute respiratory illness caused by human parainfluenza viruses.},
  author={Henrick Schomacker and Anne Schaap-Nutt and Peter L. Collins and Alexander C. Schmidt},
  journal={Current opinion in virology},
  volume={2 3},
Human parainfluenza viruses (HPIVs) are a common cause of acute respiratory illness throughout life. Infants, children, and the immunocompromised are the most likely to develop severe disease. HPIV1 and HPIV2 are best known to cause croup while HPIV3 is a common cause of bronchiolitis and pneumonia. HPIVs replicate productively in respiratory epithelial cells and do not spread systemically unless the host is severely immunocompromised. Molecular studies have delineated how HPIVs evade and block… CONTINUE READING

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Chapter 42. Parainfluenza viruses

  • RA Karron, PL Collins
  • In Fields Virology,
  • 2007
Highly Influential
7 Excerpts

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