Pathogenesis of acute aortic dissection: a finite element stress analysis.

  title={Pathogenesis of acute aortic dissection: a finite element stress analysis.},
  author={Derek P Nathan and Chun Xu and Joseph H. Gorman and Ron M Fairman and Joseph E. Bavaria and Robert C. Gorman and Krishnan B. Chandran and Benjamin M. Jackson},
  journal={The Annals of thoracic surgery},
  volume={91 2},
BACKGROUND Type A and type B aortic dissections typically result from intimal tears above the sinotubular junction and distal to the left subclavian artery (LSA) ostium, respectively. We hypothesized that this pathology results from elevated pressure-induced regional wall stress. METHODS We identified 47 individuals with normal thoracic aortas by electrocardiogram-gated computed tomography angiography. The thoracic aorta was segmented, reconstructed, and triangulated to create a geometric… CONTINUE READING