Pathogenesis of abnormal acid-base balance in the young spontaneously hypertensive rat.

@article{Lucas1988PathogenesisOA,
  title={Pathogenesis of abnormal acid-base balance in the young spontaneously hypertensive rat.},
  author={Philip A. Lucas and Bernard Lacour and L Comte and Tilman Bernhard Dr{\"u}eke},
  journal={Clinical science},
  year={1988},
  volume={75 1},
  pages={29-34}
}
1. We have previously reported reduced blood pH and plasma bicarbonate in young Okamoto-Aoki spontaneously hypertensive rats (SHR) compared with normotensive Wistar-Kyoto rats (WKY). Acid loading with 1.5% (w/v) NH4Cl as the sole drinking fluid produced identical falls in blood pH, the difference remaining significant. 2. The ability of SHR to excrete acid… CONTINUE READING