Pathogenesis of Gout

@article{Choi2005PathogenesisOG,
  title={Pathogenesis of Gout},
  author={Hyon K. Choi and David B. Mount and Anthony M. Reginato},
  journal={Annals of Internal Medicine},
  year={2005},
  volume={143},
  pages={499-516}
}
Clinical Principles The overall disease burden of gout is substantial and may be increasing. As more scientific data on the modifiable risk factors and comorbidities of gout become available, integration of these data into gout care strategies may become essential. Hyperuricemia and gout are associated with the insulin resistance syndrome and related comorbid conditions. Lifestyle modifications that are recommended for gout generally align with those for major chronic disorders (such as the… 
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