Pathogenesis of COPD.

@article{Spurzem2005PathogenesisOC,
  title={Pathogenesis of COPD.},
  author={J. Spurzem and S. Rennard},
  journal={Seminars in respiratory and critical care medicine},
  year={2005},
  volume={26 2},
  pages={
          142-53
        }
}
Chronic obstructive pulmonary disease (COPD) is characterized and defined by limitation of expiratory airflow. This can result from several types of anatomical lesions, including loss of lung elastic recoil and fibrosis and narrowing of small airways. Inflammation, edema, and secretions also contribute variably to airflow limitation. Smoking can cause COPD through several mechanisms. First, smoke is a powerful inducer of an inflammatory response. Inflammatory mediators, including oxidants and… Expand
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