Pathogenesis of Babesia caballi infection in experimental horses.

  title={Pathogenesis of Babesia caballi infection in experimental horses.},
  author={Yukiko Hanafusa and Kyoung Oh Cho and Takumi Kanemaru and Ruichi Wada and Chihiro Sugimoto and Misao Onuma},
  journal={The Journal of veterinary medical science},
  volume={60 10},
The present study was designed to investigate the role of cytokines in the pathogenesis of Babesia caballi in experimentally infected horses. The expression of cytokine mRNA was determined by using reverse transcription-polymerase chain reaction in two B. caballi-infected horses for 2 weeks after the infection. In one horse, there was up-regulation of interferon-gamma, tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 mRNAs, while in the second horse, expression of only TNF-alpha mRNA… CONTINUE READING


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