Pathogenesis of Afa/Dr diffusely adhering Escherichia coli.

  title={Pathogenesis of Afa/Dr diffusely adhering Escherichia coli.},
  author={Alain L. Servin},
  journal={Clinical microbiology reviews},
  volume={18 2},
Over the last few years, dramatic increases in our knowledge about diffusely adhering Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes E. coli strains harboring AfaE-I, AfaE-II, AfaE-III, AfaE-V, Dr, Dr-II, F1845, and NFA-I adhesins (Afa/Dr DAEC); these strains (i) have an identical genetic organization and (ii) allow binding to human decay-accelerating factor (DAF) (Afa/Dr(DAF) subclass) or carcinoembryonic antigen (CEA) (Afa/Dr(CEA) subclass). The… CONTINUE READING