Pathogenesis and treatment concepts of orthopaedic biofilm infections.


Implant-associated infection is caused by surface-adhering bacteria persisting as biofilm. Periprosthetic joint infection is difficult to diagnose and treat. The high susceptibility of implanted devices to infection is because of a locally acquired host defense defect, and persistence is mainly because of the rapid formation of a biofilm resistant to host… (More)
DOI: 10.1111/j.1574-695X.2012.00938.x


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