Pathogenesis and therapy of focal segmental glomerulosclerosis: an update

Abstract

Focal and segmental glomerulosclerosis (FSGS) is an important cause of steroid-resistant nephrotic syndrome in adults and children. It is responsible for 5–20% of all cases of end-stage kidney disease (ESKD) in the United States. The pathogenesis of FSGS has not been fully elucidated; however, data from molecular studies of familial cases in the last two… (More)
DOI: 10.1007/s00467-010-1692-x

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