Pathogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury.

Abstract

OBJECTIVE Experimental models and clinical observations of acute spinal cord injury (SCI) support the concepts of primary and secondary injury, in which the initial mechanical insult is succeeded by a series of deleterious events that promote progressive tissue damage and ischemia. Whereas the primary injury is fated by the circumstances of the trauma, the… (More)

Topics

  • Presentations referencing similar topics