Pathogenesis and management of irritable bowel syndrome.


The exact cause of irritable bowel syndrome (IBS) is not known. Multiple factors, like genetic, gut motility, visceral hypersensitivity, psychosocial factors and immune-mediated factors, are thought to contribute to the symptom complex of IBS. Till date an 'IBS gene' has not been defined, and there is a need for further studies. The concept that IBS as a… (More)