Pathogenesis and immunity in enterococcal infections.

  title={Pathogenesis and immunity in enterococcal infections.},
  author={Irina G. Sava and Esther Heikens and Johannes Huebner},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  volume={16 6},
Enterococcus faecalis and Enterococcus faecium have emerged as multi-resistant nosocomial pathogens in immunocompromised and critically ill patients. Multi-resistant strains have acquired virulence genes resulting in hospital-adapted clones. The following review summarizes several proteins and carbohydrate- or glycoconjugates that have been identified as putative virulence factors involved in the pathogenesis of enterococcal infections and may be used as targets for alternative therapies… CONTINUE READING
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