Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus

@inproceedings{Safronetz2011PathogenesisAH,
  title={Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus},
  author={David Safronetz and Marko Zivcec and Rachel A. Lacasse and Friederike Feldmann and Rebecca Rosenke and Dan Long and Elaine Haddock and Douglas L Brining and Donald Gardner and Heinz Feldmann and Hideki Ebihara},
  booktitle={PLoS pathogens},
  year={2011}
}
Hantavirus pulmonary syndrome (HPS), also referred to as hantavirus cardiopulmonary syndrome (HCPS), is a rare but frequently fatal disease caused by New World hantaviruses. In humans HPS is associated with severe pulmonary edema and cardiogenic shock; however, the pathogenesis of this disease remains unclear largely due to a lack of suitable animal models for the study of disease progression. In this study we monitored clinical, virological, pathophysiological parameters and host immunological… CONTINUE READING

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