Pathogen typing in the genomics era: MLST and the future of molecular epidemiology.

@article{PrezLosada2013PathogenTI,
  title={Pathogen typing in the genomics era: MLST and the future of molecular epidemiology.},
  author={Marcos P{\'e}rez-Losada and Patricia Cabezas and Eduardo Castro-Nallar and Keith A. Crandall},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2013},
  volume={16},
  pages={38-53}
}
Multi-locus sequence typing (MLST) is a high-resolution genetic typing approach to identify species and strains of pathogens impacting human health, agriculture (animals and plants), and biosafety. In this review, we outline the general concepts behind MLST, molecular approaches for obtaining MLST data, analytical approaches for MLST data, and the contributions MLST studies have made in a wide variety of areas. We then look at the future of MLST and their relative strengths and weaknesses with… CONTINUE READING
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