Pathogen inactivation and removal procedures used in the production of intravenous immunoglobulins.

@article{Kempf2007PathogenIA,
  title={Pathogen inactivation and removal procedures used in the production of intravenous immunoglobulins.},
  author={Christoph Kempf and M. J. Stucki and Nicola Boschetti},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2007},
  volume={35 1},
  pages={35-42}
}
Patients with immunodeficiencies or some types of autoimmune diseases rely on a safe therapy with intravenous immunoglobulins (IVIGs) manufactured from human plasma, the only available source for this therapeutic. Since plasma is predisposed to contamination by a variety of blood-borne pathogens, ascertaining and ensuring the pathogen safety of plasma-derived therapeutics is a priority among manufacturers. State-of-the-art manufacturing processes provide a high safety standard by incorporating… CONTINUE READING